Hailed as a visionary and a technological genius, Steve Jobs' death prompted several Fortune 500 company CEOs, celebrities, politicians, fellow tech-savvy experts and Apple lovers to offer their condolences and praises of Jobs' life accomplishments.
Apple, Inc. also launched a shout-out tribute page on their website, Apple.com, inviting all to share their "thoughts, memories and condolences."
Jobs died on Wednesday. He was 56.
Pancreatic cancer is one of the faster spreading cancers; only about 4% of patients can expect to survive five years after their diagnosis. Each year, about 44,000 new cases are diagnosed in the U.S., and 37,000 people die of the disease.
The pancreas contains two types of glands: exocrine glands that produce enzymes that break down fats and proteins, and endocrine glands that make hormones like insulin that regulate sugar in the blood. Jobs died of tumors originating in the endocrine glands, which are among the rarer forms of pancreatic cancer.
IN MEMORIAM: Technology's Great Reinventor: Steve Jobs (1955-2011)
In 2004, Jobs underwent surgery to remove the cancer from his pancreas. In 2009, after taking another leave of absence from Apple, Jobs had a liver transplant in an effort to retain as much of his organ function as possible after his cancer had spread beyond the pancreas. In January, he took a third leave from the company before resigning as CEO in August.
"I have always said if there ever came a day when I could no longer meet my duties and expectations as Apple's CEO, I would be the first to let you know," Jobs wrote in a letter to the Apple board of directors on August 24. "Unfortunately, that day has come."
According to experts, Jobs' was an uphill medical battle. "He not only had cancer, he was battling the immune suppression after the liver transplant," Dr. Timothy Donahue of the UCLA Center for Pancreatic Disease in Los Angeles, who had not treated Jobs, told MSNBC.com. He noted that most patients who receive liver transplants survive about two years after the surgery.
Standard treatments for pancreatic cancer include the common tumor-fighting strategies — surgery, chemotherapy, radiation and, most recently, targeted anticancer drugs that may slightly extend patients' lives. In 2005, the Food and Drug Administration approved erlotinib, a drug that specifically targets growth factors found on cancer cells, for the treatment of patients with advanced pancreatic cancer who are receiving chemotherapy. The drug has been shown in trials to improve overall survival by 23% after a year when added to routine chemotherapy. The tumors in patients being treated with erlotinib and chemo also develop more slowly than those in patients receiving chemotherapy alone.
PHOTOS: The Long, Extraordinary Career of Steve Jobs
Because of the poor prognosis of pancreatic cancer, however, many patients elect to try alternative therapies, including a popular therapy known as the Gonzalez regimen, which involves fighting pancreatic tumors with pancreatic enzymes. Patients on the Gonzalez regimen also take a large number of nutritional supplements, including vitamins and minerals such as magnesium citrate, along with coffee enemas performed twice a day.
The treatment's developer, Dr. Nicholas Gonzalez of New York, has claimed that the use of pancreatic enzymes is a powerful way to suppress the growth of advanced pancreatic cancer cells. But a study published in the Journal of Clinical Oncology in 2009, which compared groups of patients on the Gonzalez regiment to patients on standard chemotherapy treatment, found that those on chemo survived for a median of 14 months while those on the alternative therapy survived for a median of only 4.3 months.
Jobs is not reported to have tried the Gonzalez regimen, but he is known to have suscribed to alternative therapy. In a 2008 story, Fortune reported that Jobs initially tried to treat his tumor with diet instead of surgery, soon after he was diagnosed in 2004. In January, Fortune reported that he had also made a hush-hush trip to Switzerland in 2009 for a radiation-based hormone treatment. The exact details aren't clear, but the University Hospital of Basel in Switzerland is known for its special form of treatment for neuroendocrine cancer, which is not available in the U.S.
Whether these treatments helped to extend Jobs' life or improve the quality of his last days isn't clear. But cancer experts expressed surprise that Jobs survived as long as he did, continuing to fight his disease. Other pancreatic cancer patients typically aren't as fortunate. Another high-profile patient, actor Patrick Swayze, managed to live for 20 months after his diagnosis, taking advantage of chemotherapy treatments. But, overall, patients' median survival is generally only five months.
VIDEO: Steve Jobs' Career at Apple (in Two Minutes)
Jobs lost his battle with cancer at a time when researchers are constantly pushing the boundaries of treatments, particularly with antitumor agents that can home in on abnormally growing cells with increasing precision. In the end, his cancer proved too advanced to rein in with even the most innovative technologies.
"Apple has lost a visionary and creative genius, and the world has lost an amazing human being," Tim Cook, Jobs' successor at Apple, wrote to employees on Wednesday. "Steve leaves behind a company that only he could have built, and his spirit will forever be the foundation of Apple."
By the time Rakesh Achanta and Chris Young, two electrical engineering masters students at Stanford, got to Steve Jobs' home in Palo Alto it was past midnight. "We just had to come pay homage," says Achanta, 28, from Hyderabad, India.
"He was just such a gigantic influence," echoes Young, 25, from San Antonio. (See photos of the long and extraordinary career of Steve Jobs.)
The two squint in the candlelight at the chalk and crayon messages of love and condolences scrawled across the sidewalk in front of the English country home, just a block and a half from Google CEO Larry Page's house. Flowers line the wooden fence, behind which stand three apple trees just dropping their fruit. On several of the fence posts, fans have placed apples with one bite taken out of them, a reference to the Apple logo. Interspersed amongst the flowers are iPhone boxes wrapped with notes and even a first-generation iPod with "Steve Jobs 1955-2011" written on it in black marker.
Since the announcement Wednesday evening that Jobs, 56, co-founder and chairman of Apple, had died, a steady stream of visitors have come to his home to pay their respects. Police barriers block vehicular traffic down a side road, but otherwise people are allowed to wander around the property where Jobs' wife Laurene and their three children still reside. That night, a similar scene was playing out at two other locations across town. At the Apple Store Jobs himself used to frequent a mile-and-a-half away on Palo Alto's main drag, people left candles, poems — some slightly singed from the flickering flames — and flowers. Steve Jobs/ the pursuit of beauty and excellence/ demanding perfect ..." read the beginning of one lengthy tribute. (See photos of Steve Jobs' TIME covers.)
But the biggest memorial was at Apple headquarters at 1 Infinite Loop in Cupertino 10 miles away, where seven satellite trucks tracked people streaming through with flowers, balloons and mementos. Six Chinese computer science students from nearby colleges used tea candles to created a big Apple logo and write "Jobs" in English and Chinese on the pavement. At the foot of a bench, swamped with flowers and condolences, red candle wax ran in rivulets along the pavement grooves. "You can read about Gandhi, about people of that level, but it's rare that you could interact with them, meet them," says Ishdeep Sawhney, a software developer for Apple originally from Delhi. "We all knew his health wasn't doing well, but this was a shock." Sawhney, accompanied by his teary wife Bino Kohli, a product developer at Oracle, had come to pay his respects to the man whose sheer work ethic lured Sawhney from Microsoft five years ago.
Jobs announced to his employees in mid-2004 that he'd been diagnosed with pancreatic cancer. In April 2009, he underwent a liver transplant. And then in August, he announced his resignation as CEO due to health reasons. On Monday, he succumbed to an unknown disease in the presence of his family. "We'll miss you, Steve," read one thank you card. "We believe that people with passion can change the world for the better." (See a two-minute video of Steve Jobs' career.)
Jobs certainly didn't lack in passion. He was an infamously demanding boss. "I can't decide whether or not to be sad," said one employee who didn't want to be named, walking up to the office memorial. But he was unquestionably brilliant. "He was a big influence on my life," says Richard Jordan, 39, a Brit who works in tech start ups and used to know Jobs as a neighbor in Palo Alto. "He was a big influence on most people's lives around here. He was one of Silicon Valley's founding fathers."
In recent years Jobs has given the world the iPod, iPhone, iPad, and iCloud. But perhaps the biggest loss is of the innovations he'd yet to realize. He also didn't live to see his new home or offices completed — both are in the works. In fact, it was his charging ahead with the new projects that had led many close Jobs watchers — he was infamously private - to speculate that his health wasn't that bad. But, clearly, it was.
"Who knows, Chris, maybe you're the next Steve Jobs," electrical engineering student Achanta said to his fellow mourner outside Jobs' Palo Alto home. "Yeah, and you're Woz," Young shot back, referring to Apple co-founder Steve Wozniak. (See the top 10 Apple moments.)
But Achanta was already reconsidering. "But you wouldn't want to die at 56. I know I wouldn't," he mused. "Though, I suppose I would if I could make an impact like Jobs did. Okay, I'd be the next Steve." By half-past midnight the pair were on their way back to school, having left a note on the only piece of paper they had, a Post It. It read: "An apple falls to the ground to become a shade-giving tree."
Here are their words:
Apple, Inc. also launched a shout-out tribute page on their website, Apple.com, inviting all to share their "thoughts, memories and condolences."
Jobs died on Wednesday. He was 56.
The Pancreatic Cancer That Killed Steve Jobs
In their announcement of founder Steve Jobs' death, at age 56, Apple officials did not mention a specific cause of death. But the visionary digital leader had been battling pancreatic cancer since 2004.Pancreatic cancer is one of the faster spreading cancers; only about 4% of patients can expect to survive five years after their diagnosis. Each year, about 44,000 new cases are diagnosed in the U.S., and 37,000 people die of the disease.
The pancreas contains two types of glands: exocrine glands that produce enzymes that break down fats and proteins, and endocrine glands that make hormones like insulin that regulate sugar in the blood. Jobs died of tumors originating in the endocrine glands, which are among the rarer forms of pancreatic cancer.
IN MEMORIAM: Technology's Great Reinventor: Steve Jobs (1955-2011)
In 2004, Jobs underwent surgery to remove the cancer from his pancreas. In 2009, after taking another leave of absence from Apple, Jobs had a liver transplant in an effort to retain as much of his organ function as possible after his cancer had spread beyond the pancreas. In January, he took a third leave from the company before resigning as CEO in August.
"I have always said if there ever came a day when I could no longer meet my duties and expectations as Apple's CEO, I would be the first to let you know," Jobs wrote in a letter to the Apple board of directors on August 24. "Unfortunately, that day has come."
According to experts, Jobs' was an uphill medical battle. "He not only had cancer, he was battling the immune suppression after the liver transplant," Dr. Timothy Donahue of the UCLA Center for Pancreatic Disease in Los Angeles, who had not treated Jobs, told MSNBC.com. He noted that most patients who receive liver transplants survive about two years after the surgery.
Standard treatments for pancreatic cancer include the common tumor-fighting strategies — surgery, chemotherapy, radiation and, most recently, targeted anticancer drugs that may slightly extend patients' lives. In 2005, the Food and Drug Administration approved erlotinib, a drug that specifically targets growth factors found on cancer cells, for the treatment of patients with advanced pancreatic cancer who are receiving chemotherapy. The drug has been shown in trials to improve overall survival by 23% after a year when added to routine chemotherapy. The tumors in patients being treated with erlotinib and chemo also develop more slowly than those in patients receiving chemotherapy alone.
PHOTOS: The Long, Extraordinary Career of Steve Jobs
Because of the poor prognosis of pancreatic cancer, however, many patients elect to try alternative therapies, including a popular therapy known as the Gonzalez regimen, which involves fighting pancreatic tumors with pancreatic enzymes. Patients on the Gonzalez regimen also take a large number of nutritional supplements, including vitamins and minerals such as magnesium citrate, along with coffee enemas performed twice a day.
The treatment's developer, Dr. Nicholas Gonzalez of New York, has claimed that the use of pancreatic enzymes is a powerful way to suppress the growth of advanced pancreatic cancer cells. But a study published in the Journal of Clinical Oncology in 2009, which compared groups of patients on the Gonzalez regiment to patients on standard chemotherapy treatment, found that those on chemo survived for a median of 14 months while those on the alternative therapy survived for a median of only 4.3 months.
Jobs is not reported to have tried the Gonzalez regimen, but he is known to have suscribed to alternative therapy. In a 2008 story, Fortune reported that Jobs initially tried to treat his tumor with diet instead of surgery, soon after he was diagnosed in 2004. In January, Fortune reported that he had also made a hush-hush trip to Switzerland in 2009 for a radiation-based hormone treatment. The exact details aren't clear, but the University Hospital of Basel in Switzerland is known for its special form of treatment for neuroendocrine cancer, which is not available in the U.S.
Whether these treatments helped to extend Jobs' life or improve the quality of his last days isn't clear. But cancer experts expressed surprise that Jobs survived as long as he did, continuing to fight his disease. Other pancreatic cancer patients typically aren't as fortunate. Another high-profile patient, actor Patrick Swayze, managed to live for 20 months after his diagnosis, taking advantage of chemotherapy treatments. But, overall, patients' median survival is generally only five months.
VIDEO: Steve Jobs' Career at Apple (in Two Minutes)
Jobs lost his battle with cancer at a time when researchers are constantly pushing the boundaries of treatments, particularly with antitumor agents that can home in on abnormally growing cells with increasing precision. In the end, his cancer proved too advanced to rein in with even the most innovative technologies.
"Apple has lost a visionary and creative genius, and the world has lost an amazing human being," Tim Cook, Jobs' successor at Apple, wrote to employees on Wednesday. "Steve leaves behind a company that only he could have built, and his spirit will forever be the foundation of Apple."
Steve Jobs: Silicon Valley Mourns the Death of a Founding Father
"We will miss you, R.I.P. Steve Jobs" is
written on the sidewalk outside the the home of Steve Jobs in Palo Alto,
California, October 5, 2011
Beck Diefenbach / Reuters
By the time Rakesh Achanta and Chris Young, two electrical engineering masters students at Stanford, got to Steve Jobs' home in Palo Alto it was past midnight. "We just had to come pay homage," says Achanta, 28, from Hyderabad, India.
"He was just such a gigantic influence," echoes Young, 25, from San Antonio. (See photos of the long and extraordinary career of Steve Jobs.)
The two squint in the candlelight at the chalk and crayon messages of love and condolences scrawled across the sidewalk in front of the English country home, just a block and a half from Google CEO Larry Page's house. Flowers line the wooden fence, behind which stand three apple trees just dropping their fruit. On several of the fence posts, fans have placed apples with one bite taken out of them, a reference to the Apple logo. Interspersed amongst the flowers are iPhone boxes wrapped with notes and even a first-generation iPod with "Steve Jobs 1955-2011" written on it in black marker.
Since the announcement Wednesday evening that Jobs, 56, co-founder and chairman of Apple, had died, a steady stream of visitors have come to his home to pay their respects. Police barriers block vehicular traffic down a side road, but otherwise people are allowed to wander around the property where Jobs' wife Laurene and their three children still reside. That night, a similar scene was playing out at two other locations across town. At the Apple Store Jobs himself used to frequent a mile-and-a-half away on Palo Alto's main drag, people left candles, poems — some slightly singed from the flickering flames — and flowers. Steve Jobs/ the pursuit of beauty and excellence/ demanding perfect ..." read the beginning of one lengthy tribute. (See photos of Steve Jobs' TIME covers.)
But the biggest memorial was at Apple headquarters at 1 Infinite Loop in Cupertino 10 miles away, where seven satellite trucks tracked people streaming through with flowers, balloons and mementos. Six Chinese computer science students from nearby colleges used tea candles to created a big Apple logo and write "Jobs" in English and Chinese on the pavement. At the foot of a bench, swamped with flowers and condolences, red candle wax ran in rivulets along the pavement grooves. "You can read about Gandhi, about people of that level, but it's rare that you could interact with them, meet them," says Ishdeep Sawhney, a software developer for Apple originally from Delhi. "We all knew his health wasn't doing well, but this was a shock." Sawhney, accompanied by his teary wife Bino Kohli, a product developer at Oracle, had come to pay his respects to the man whose sheer work ethic lured Sawhney from Microsoft five years ago.
Jobs announced to his employees in mid-2004 that he'd been diagnosed with pancreatic cancer. In April 2009, he underwent a liver transplant. And then in August, he announced his resignation as CEO due to health reasons. On Monday, he succumbed to an unknown disease in the presence of his family. "We'll miss you, Steve," read one thank you card. "We believe that people with passion can change the world for the better." (See a two-minute video of Steve Jobs' career.)
Jobs certainly didn't lack in passion. He was an infamously demanding boss. "I can't decide whether or not to be sad," said one employee who didn't want to be named, walking up to the office memorial. But he was unquestionably brilliant. "He was a big influence on my life," says Richard Jordan, 39, a Brit who works in tech start ups and used to know Jobs as a neighbor in Palo Alto. "He was a big influence on most people's lives around here. He was one of Silicon Valley's founding fathers."
In recent years Jobs has given the world the iPod, iPhone, iPad, and iCloud. But perhaps the biggest loss is of the innovations he'd yet to realize. He also didn't live to see his new home or offices completed — both are in the works. In fact, it was his charging ahead with the new projects that had led many close Jobs watchers — he was infamously private - to speculate that his health wasn't that bad. But, clearly, it was.
"Who knows, Chris, maybe you're the next Steve Jobs," electrical engineering student Achanta said to his fellow mourner outside Jobs' Palo Alto home. "Yeah, and you're Woz," Young shot back, referring to Apple co-founder Steve Wozniak. (See the top 10 Apple moments.)
But Achanta was already reconsidering. "But you wouldn't want to die at 56. I know I wouldn't," he mused. "Though, I suppose I would if I could make an impact like Jobs did. Okay, I'd be the next Steve." By half-past midnight the pair were on their way back to school, having left a note on the only piece of paper they had, a Post It. It read: "An apple falls to the ground to become a shade-giving tree."
Here are their words:
Statement from President Barack Obama
"Michelle and I are saddened to learn of the passing of Steve Jobs. Steve was among the greatest of American innovators - brave enough to think differently, bold enough to believe he could change the world, and talented enough to do it.
By building one of the planet's most successful companies from his garage, he exemplified the spirit of American ingenuity. By making computers personal and putting the internet in our pockets, he made the information revolution not only accessible, but intuitive and fun. And by turning his talents to storytelling, he has brought joy to millions of children and grownups alike. Steve was fond of saying that he lived every day like it was his last. Because he did, he transformed our lives, redefined entire industries, and achieved one of the rarest feats in human history: he changed the way each of us sees the world.
The world has lost a visionary. And there may be no greater tribute to Steve's success than the fact that much of the world learned of his passing on a device he invented. Michelle and I send our thoughts and prayers to Steve's wife Laurene, his family, and all those who loved him."
Statement from Bill Gates
"Michelle and I are saddened to learn of the passing of Steve Jobs. Steve was among the greatest of American innovators - brave enough to think differently, bold enough to believe he could change the world, and talented enough to do it.
By building one of the planet's most successful companies from his garage, he exemplified the spirit of American ingenuity. By making computers personal and putting the internet in our pockets, he made the information revolution not only accessible, but intuitive and fun. And by turning his talents to storytelling, he has brought joy to millions of children and grownups alike. Steve was fond of saying that he lived every day like it was his last. Because he did, he transformed our lives, redefined entire industries, and achieved one of the rarest feats in human history: he changed the way each of us sees the world.
The world has lost a visionary. And there may be no greater tribute to Steve's success than the fact that much of the world learned of his passing on a device he invented. Michelle and I send our thoughts and prayers to Steve's wife Laurene, his family, and all those who loved him."
Statement from Bill Gates
"I'm
truly saddened to learn of Steve Jobs' death. Melinda and I extend our
sincere condolences to his family and friends, and to everyone Steve has
touched through his work.
Steve and I first met nearly 30 years ago, and have been colleagues, competitors and friends over the course of more than half our lives.
The world rarely sees someone who has had the profound impact Steve has had, the effects of which will be felt for many generations to come.
For those of us lucky enough to get to work with him, it's been an insanely great honor. I will miss Steve immensely. "
Steve and I first met nearly 30 years ago, and have been colleagues, competitors and friends over the course of more than half our lives.
The world rarely sees someone who has had the profound impact Steve has had, the effects of which will be felt for many generations to come.
For those of us lucky enough to get to work with him, it's been an insanely great honor. I will miss Steve immensely. "
Statement from Jerry Yang, Yahoo! founder
"Steve was my hero growing up. He not only gave me a lot of personal advice and encouragement, he showed all of us how innovation can change lives. I will miss him dearly, as will the world."
Statement from Mark Zuckerberg, Facebook founder and CEO
"Steve,
thank you for being a mentor and a friend. Thanks for showing that what
you build can change the world. I will miss you."
Statement from Microsoft co-founder Paul Allen
"My condolences to Steve Jobs family and friends. We've lost a unique tech pioneer and auteur who knew how to make amazingly great products."
Statement from House Minority Leader Nancy Pelosi, D-Calif.
Statement from Microsoft co-founder Paul Allen
"My condolences to Steve Jobs family and friends. We've lost a unique tech pioneer and auteur who knew how to make amazingly great products."
Statement from House Minority Leader Nancy Pelosi, D-Calif.
"Steve
Jobs was a visionary who changed the way we live, an innovator whose
products brought joy to millions, a risktaker who wasn't afraid to
challenge the status quo, and an entrepreneur who led one of the most
creative companies of our time.
"His sage advice was respected by policymakers on both sides of the aisle. His courageous fight against cancer brought strength to many.
"I hope it is a comfort to those who loved him, especially his family, that so many grieve his loss and are praying for them at this sad time."
Statement from Walt Disney president Bob Iger
"His sage advice was respected by policymakers on both sides of the aisle. His courageous fight against cancer brought strength to many.
"I hope it is a comfort to those who loved him, especially his family, that so many grieve his loss and are praying for them at this sad time."
Statement from Walt Disney president Bob Iger
"Steve
Jobs was a great friend as well as a trusted advisor. His legacy will
extend far beyond the products he created or the businesses he built. It
will be the millions of people he inspired, the lives he changed, and
the culture he defined. Steve was such an "original," with a thoroughly
creative, imaginative mind that defined an era. Despite all he
accomplished, it feels like he was just getting started. With his
passing the world has lost a rare original, Disney has lost a member of
our family, and I have lost a great friend. Our thoughts and prayers are
with his wife Laurene and his children during this difficult time."
Statement from California Gov. Edmund Brown
"Steve Jobs was a great California innovator who demonstrated what a totally independent and creative mind can accomplish. Few people have made such a powerful and elegant imprint on our lives. Anne and I wish to express our deepest sympathy to Steve's wife, Laurene, and their entire family."
Statement from New York City Mayor Michael Bloomberg
Statement from California Gov. Edmund Brown
"Steve Jobs was a great California innovator who demonstrated what a totally independent and creative mind can accomplish. Few people have made such a powerful and elegant imprint on our lives. Anne and I wish to express our deepest sympathy to Steve's wife, Laurene, and their entire family."
Statement from New York City Mayor Michael Bloomberg
"Tonight,
America lost a genius who will be remembered with Edison and Einstein,
and whose ideas will shape the world for generations to come. Again and
again over the last four decades, Steve Jobs saw the future and brought
it to life long before most people could even see the horizon. And
Steve's passionate belief in the power of technology to transform the
way we live brought us more than smart phones and iPads: it brought
knowledge and power that is reshaping the face of civilization. In New
York City's government, everyone from street construction inspectors to
NYPD detectives have harnessed Apple's
products to do their jobs more efficiently and intuitively. Tonight our
City - a city that has always had such respect and admiration for
creative genius - joins with people around the planet in remembering a
great man and keeping Laurene and the rest of the Jobs family in our
thoughts and prayers."
Celebrities and Politicians Take to Twitter to Offer Condolences
Celebrities and Politicians Take to Twitter to Offer Condolences
Arianna Huffington, Huffington Post CEO
"@ariannahuff: My thoughts go out to Steve Jobs' family and friends. Thank you for changing our world."
Steve Levitan, co-creator/executive producer of ABC's "Modern Family"
"@SteveLevitan: I'm so sorry to hear about the death of Steve Jobs. He was truly one of my heroes. He leaves one hell of a legacy. #iSad"
Former California Gov. Arnold Schwarzenegger
"@Schwarzenegger: Steve lived the California Dream every day of his life and he changed the world and inspired all of us. #ThankYouSteve"
Former California first lady Maria Shriver
"@mariashriver: I'm going to turn off my Apple computer, iPhone and iPad tonight at 8pm and honor Steve with a moment of digital silence. Will you join me?"
"@mariashriver: I'm so happy that I knew him and was so blessed by his friendship. He impacted all of our lives and changed the world."
"@mariashriver: My heart weeps for all who worked with Steve and who loved him, especially my friend Laurene and their children."
Jon Huntsman, Republican presidential candidate
"@JonHuntsman: Sad to hear about the passing of Steve Jobs, a true inspiration and a great American innovator."
Ryan Seacrest, "American Idol" host/radio talk show personality/producer
"@RyanSeacrest: 'Have the courage to follow ur heart & intuition. They already know what u truly want to become. Everything else is secondary.' - Steve Jobs"
Nancy Grace, TV host, "Dancing With the Stars" contestant
"@NancyGraceHLN: About to go to air & discovered news about Steve Jobs - My heart goes out to his family tonight. #RIP Steve Jobs"
Lebron James, Miami Heat forward
"@KingJames: R.I.P Steve Jobs. Someone who definitely left his mark on this world! Innovations that will live and last forever!!"
Neil Patrick Harris, Actor on "How I Met Your Mother"
"@ActuallyNPH: Rest in peace, Steve Jobs. Your genius will live on for generations to come..."
Zach Braff, Actor
"@zachbraff: RIP Steve Jobs. A legend. A visionary innovator."
Nick Lachey, singer, host of "The Sing-Off"
"@NickSLachey: Best wishes to the family of #stevejobs. What an amazing man and amazing life! Certainly, his legacy will be with us all forever. #RIP."
"@ariannahuff: My thoughts go out to Steve Jobs' family and friends. Thank you for changing our world."
Steve Levitan, co-creator/executive producer of ABC's "Modern Family"
"@SteveLevitan: I'm so sorry to hear about the death of Steve Jobs. He was truly one of my heroes. He leaves one hell of a legacy. #iSad"
Former California Gov. Arnold Schwarzenegger
"@Schwarzenegger: Steve lived the California Dream every day of his life and he changed the world and inspired all of us. #ThankYouSteve"
Former California first lady Maria Shriver
"@mariashriver: I'm going to turn off my Apple computer, iPhone and iPad tonight at 8pm and honor Steve with a moment of digital silence. Will you join me?"
"@mariashriver: I'm so happy that I knew him and was so blessed by his friendship. He impacted all of our lives and changed the world."
"@mariashriver: My heart weeps for all who worked with Steve and who loved him, especially my friend Laurene and their children."
Jon Huntsman, Republican presidential candidate
"@JonHuntsman: Sad to hear about the passing of Steve Jobs, a true inspiration and a great American innovator."
Ryan Seacrest, "American Idol" host/radio talk show personality/producer
"@RyanSeacrest: 'Have the courage to follow ur heart & intuition. They already know what u truly want to become. Everything else is secondary.' - Steve Jobs"
Nancy Grace, TV host, "Dancing With the Stars" contestant
"@NancyGraceHLN: About to go to air & discovered news about Steve Jobs - My heart goes out to his family tonight. #RIP Steve Jobs"
Lebron James, Miami Heat forward
"@KingJames: R.I.P Steve Jobs. Someone who definitely left his mark on this world! Innovations that will live and last forever!!"
Neil Patrick Harris, Actor on "How I Met Your Mother"
"@ActuallyNPH: Rest in peace, Steve Jobs. Your genius will live on for generations to come..."
Zach Braff, Actor
"@zachbraff: RIP Steve Jobs. A legend. A visionary innovator."
Nick Lachey, singer, host of "The Sing-Off"
"@NickSLachey: Best wishes to the family of #stevejobs. What an amazing man and amazing life! Certainly, his legacy will be with us all forever. #RIP."